Left Ventricular Non-Compaction Associated With Patent Ductus Arteriosus

Isolated left ventricular non-compaction (LVNC) is a rare congenital anomaly. It is characterized by numerous prominent ventricular trabecullations and deep intertrabecular recesses. The incidences of associated cardiovascular complication and congenital heart disease are high. It is associated with congestive heart failure, ventricular arrhythmia, embolic events, and distinctive facial dysmorphism. Familial tendency has also been reported. It is believed to represent an arrest in endomyocardial morphogenesis. The prognosis for patients is grim. The most common cause of death in these patients was sudden cardiac collapse. Many patients suffered from transient ischemic attacks, pulmonary embolisms, heart failure events, pulmonary edema episodes, cardiogenic shock and sustained ventricular tachycardia. Even asymptomatic patients were still at risk of unpredictable ventricular arrhythmia and sudden cardiac collapse. We report a 36-year-old female with patent ductus arteriosus (PDA) and an incidental finding of left ventricular non-compaction. As far as we know, this is the first report of left ventricular non-compaction associated with PDA.